Tuo Wang

Publications

  1. S.D. Cady, T. Wang, and M. Hong, “Membrane-Dependent Effects of a Cytoplasmic Helix on the Structure and Drug Binding of the Influenza M2 Protein”, J. Am. Chem. Soc. 133, 11572-11579 (2011).

  2. J. Wang, C. Ma, G. Fiorin, V. Carnevale, T. Wang, F. Hu, R. A. Lamb, M. L. Klein, L. H. Pinto, M. Hong, and W. F. DeGrado, “Molecular Dynamics Simulation Directed Rational Design of Inhibitors Targeting Drug-Resistant Mutants of Influenza A Virus M2”, J. Am. Chem. Soc. 133, 12834-12841 (2011).

  3. T. Wang, S.D. Cady, and M. Hong, “NMR Determination of Protein Partitioning into Membrane Domains with Different Curvatures and Application to the Influenza M2 Protein”, Biophys. J. 102, 787-794 (2012).

  4. D. M Harris, K. Corbin, T. Wang, R. Gutierrez,  A.L. Bertolo, C. Petti, D.M. Smilgies, J. M. Estevez, D. Bonetta, B. Urbanowicz, D. Ehrhardt, C. R. Somerville, J. K.C. Rose, M. Hong, S. DeBolt, “Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1A903V and CESA3T942I of cellulose synthase”, Proc. Natl. Acad. Sci. USA 109, 4098-4103 (2012).

  5. M. Dick-Perez, T. Wang, A. Salazar, O. Zabotina, and M. Hong, “Multidimensional Solid-State NMR Studies of the Structure and Dynamics of Pectic Polysaccharides in Uniformly 13C-Labeled Arabidopsis Primary Cell Walls”, Magn. Reson. Chem. 50, 539-550 (2012).

  6. T. Wang, L. Widanapathirana, Y. Zhao and M. Hong, “Aggregation and Dynamics of Oligocholate Transporters in Phospholipid Bilayers Revealed by Solid-State NMR Spectroscopy”, Langmuir 28, 17071-17078 (2012).

  7. T. Wang, O. Zabotina, and M. Hong, “Pectin-cellulose and protein-polysaccharide  interactions in Arabidopsis primary cell walls by 2D 13C Correlation NMR”, Biochemistry 51, 9846-9856 (2012).

  8. T. Wang, H. Yao and M. Hong, “Determining the Depth of Insertion of Dynamically Invisible Membrane Peptides by Gel-Phase 1H Spin Diffusion Heteronuclear Correlation NMR”, J. Biomol. NMR 56, 139-148 (2013).

  9. T. Wang, Y.B. Park, M.A. Caporini, M. Rosay, D.J. Cosgrove and M. Hong, “Sensitivity-Enhanced Solid-State NMR Elucidation of Protein Binding to Cell Walls”, Proc. Natl. Acad. Sci. USA 110, 16444-9 (2013).

  10. T. Wang, O. Zabotina, and M. Hong, “Structure and Dynamics of Brachypodium Primary Cell Wall Polysaccharides From Solid-State NMR Spectroscopy”, Biochemistry 53, 2840-2854 (2014).

  11. P. B. White*, T. Wang*, Y.B. Park, D.C. Cosgrove and M. Hong, “Hydration of Cellulose and Matrix Polysaccharides in the Primary Cell Wall of Arabidopsis Thaliana from Spin Diffusion NMR”, J. Am. Chem. Soc. 136, 10399-409 (2014). *equal contributions.

  12. N. Joh, T. Wang, M. Bhate, R. Acharya, Y. Wu, M. Grabe, M. Hong, G. Grigoryan and W.F. DeGrado, “De Novo Design of a Transmembrane Zn(II) Transporting Four-Helix Bundle”, Science 346, 1520-1524 (2014).

  13. T. Wang*, J.K. Williams*, K. Schmidt-Rohr and M. Hong, “Relaxation-Compensated Difference Spin Diffusion NMR for Detecting 13C-13C Long-Range Correlations in Proteins and Polysaccharides”, J. Biomol. NMR, 61, 97-107 (2015). *equal contributions.

  14. T. Wang and M. Hong, "Investigation of the Curvature Induction and Membrane Localization of the Influenza Virus M2 Protein Using Static and Off-Magic-Angle-Spinning Solid-State Nuclear Magnetic Resonance of Oriented Bicelles", Biochemistry, 54, 2214-2226 (2015).

  15. T. Wang, Y.B. Park, D.J. Cosgrove, and M. Hong, “Cellulose-Pectin Spatial Contacts are Inherent to Never-dried Arabidopsis thaliana Primary Cell Walls: Evidence from Solid-State NMR”, Plant Physiol. 168, 871-884 (2015).

  16. T. Wang and M. Hong, “Solid-State NMR Investigations of Cellulose Structure and Interactions with Matrix Polysaccharides in Plant Primary Cell Walls", J. Exp. Bot., 67, 503-514 (2016).

  17. S. Liao, M. Lee, T. Wang. I.V. Sergeyev and M. Hong, “Efficient DNP NMR of Membrane Proteins: Sample Preparation Protocols, Sensitivity, and Radical Location", J. Biomol. NMR, 64, 223-237 (2016).

  18. T. Wang, H. Yang, J. D. Kubicki and M. Hong, “Cellulose Structural Polymorphism in Plant Primary Cell Walls Investigated by High-Field 2D Solid-State NMR Spectroscopy and Density Functional Theory Calculations", Biomacromolecules, 17, 2210-2222 (2016).

  19. M Elkins*, T Wang*, M Nick, H Jo, T Lemmin, S Prusiner, WF DeGrado, J Stohr, M. Hong, "Structural Polymorphism of Alzheimer's Beta-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study", J. Am. Chem. Soc. 138, 9840-9852. *equal contributions.

  20. T Wang, P Phyo, M. Hong, "Multidimensional Solid-State NMR Spectroscopy of Plant Cell Walls", Solid State Nucl. Magn. Reson. 78, 56-63 (2016).

  21. T. Wang, Y. Chen, A. Tabuchi, D.J. Cosgrove and M. Hong, "The Target of Beta-Expansin EXPB1 in Maize Cell Walls from Binding and Solid-State NMR Studies", Plant Physiol. 172, 2107-2119 (2016).

  22. T. Wang, H. Jo, W.F. DeGrado, M. Hong, "Water Distribution, Dynamics and Interactions with Alzheimer's Beta-Amyloid Fibrils Investigated by Solid-State NMR", J. Am. Chem. Soc. 139 (17), 6242-6252 (2017).

  23. M. Lee, T. Wang, O. V. Makhlynets, Y. Wu, N. Polizzi, H. Wu, J. Stöhr, I. V. Korendovych, W. F. DeGrado, and M. Hong*, “Zinc-Binding Structure of a Catalytic Amyloid from Solid-State NMR Spectroscopy”, PNAS, 114 (24), 6191-6196 (2017).

  24. T. Wang and M. Hong, “Structure and Dynamics of Polysaccharides in Plant Cell Walls From Solid-State NMR”, Chapter 13, NMR in Glycoscience and Glycotechnology, Royal Society of Chemistry (2017). 

  25. M. D. Gelenter, T. Wang, S. Liao, H. O'Neill, M. Hong, "2H-13C Correlation Solid-State NMR for Investigating Dynamics and Water Accessibilities of Proteins and Carbohydrates", J. Biomol. NMR. Online First Article (2017).